When Good Absorption Doesn’t Matter

Good intestinal absorption is looked upon with favor by both researchers and clinicians.  Often, it predicts lower, more affordable dosing and improved efficacy.  But absorption is not always a relevant matter.  There are 3 situations in which good absorption is less important: The affinity for the molecular target is high.  A stronger interaction with the target (nanomolar EC50 or … Continue reading When Good Absorption Doesn’t Matter